Can self-relevant stimuli help assessing patients with disorders of consciousness?

نویسندگان

  • Renata del Giudice
  • Christine Blume
  • Malgorzata Wislowska
  • Julia Lechinger
  • Dominik P.J. Heib
  • Gerald Pichler
  • Johann Donis
  • Gabriele Michitsch
  • Maria-Teresa Gnjezda
  • Mauricio Chinchilla
  • Calixto Machado
  • Manuel Schabus
چکیده

Emotional and self-relevant stimuli are able to automatically attract attention and their use in patients suffering from disorders of consciousness (DOC) might help detecting otherwise hidden signs of cognition. We here recorded EEG in three Locked-in syndrome (LIS) and four Vegetative State/Unresponsive Wakefulness Syndrome (VS/UWS) patients while they listened to the voice of a family member or an unfamiliar voice during a passive. Data indicate that, in a passive listening condition, the familiar voice induces stronger alpha desynchronization than the unfamiliar one. In an active condition, the target evoked stronger alpha desynchronization in controls, two LIS patients and one VS/UWS patient. Results suggest that self-relevant familiar voice stimuli can engage additional attentional resources and might allow the detection of otherwise hidden signs of instruction-following and thus residual awareness. Further studies are necessary to find sensitive paradigms that are suited to find subtle signs of cognition and awareness in DOC patients.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Promoting the use of personally relevant stimuli for investigating patients with disorders of consciousness

Sensory stimuli are used to evaluate and to restore cognitive functions and consciousness in patients with a disorder of consciousness (DOC) following a severe brain injury. Although sophisticated protocols can help assessing higher order cognitive functions and awareness, one major drawback is their lack of sensitivity. The aim of the present review is to show that stimulus selection is crucia...

متن کامل

A Review of Methods for Assessing the Care Needs of Patients with Disabilities

Introduction: The care needs of patients with disabilities are often neglected or not fully identified. Knowing the different methods of assessment can help the care team to choose the best and most comprehensive method of assessing care needs. Methods: This scoping review study was designed and implemented with a 5-step Arksey & O'Malley approach. the search strategy was set using the keywords...

متن کامل

The Effect of Sensory Stimuli With a Familiar Voice and Patient’s Auditory Preferences on the Level of Consciousness of Brain Injury Patients Admitted to Intensive Care Units

Background & Aims: Most patients with brain injury experience coma based on the severity of the lesion. One of the complications that threaten patients with coma in intensive care units is the risk of sensory deprivation. Frequent sensory stimulation can be helpful in rehabilitation and increasing the level of consciousness of these patients. This study aimed to determine the effect of sensory ...

متن کامل

Self-consciousness in non-communicative patients.

The clinical and para-clinical examination of residual self-consciousness in non-communicative severely brain damaged patients (i.e., coma, vegetative state and minimally conscious state) remains exceptionally challenging. Passive presentation of the patient's own name and own face are known to be effective attention-grabbing stimuli when clinically assessing consciousness at the patient's beds...

متن کامل

The reliability of the N400 in single subjects: Implications for patients with disorders of consciousness

Functional neuroimaging assessments of residual cognitive capacities, including those that support language, can improve diagnostic and prognostic accuracy in patients with disorders of consciousness. Due to the portability and relative inexpensiveness of electroencephalography, the N400 event-related potential component has been proposed as a clinically valid means to identify preserved lingui...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Consciousness and Cognition

دوره 44  شماره 

صفحات  -

تاریخ انتشار 2016